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Can Soil Microbes Really Help Solve the Resistance Crisis?

  • slr1101
  • Dec 12, 2025
  • 1 min read

Updated: Dec 16, 2025

Antibiotic resistance is one of the biggest public health challenges of our time. Bacteria are evolving faster than we can develop new antibiotics, and infections that were once easily treatable are becoming dangerous again. So where do we turn when modern medicine starts to run out of options?

Surprisingly, one promising answer might be right beneath our feet.....the soil!

What is Antibiotic Resistance?

Well, antibiotics work by killing bacteria or stopping them from growing, but bacteria don’t just sit back and accept defeat. The bacteria fight back! Through mutations and gene exchange, they can develop resistance, making treatments less effective over time.



Overuse and misuse of antibiotics in medicine and agriculture have accelerated this process, creating resistant “superbugs” that are increasingly hard to treat.

What makes this crisis even scarier is that the discovery of new antibiotics has slowed dramatically. Many pharmaceutical companies have moved away from antibiotic research because it’s expensive, time-consuming, and not as profitable as other drugs. That leaves scientists searching for new solutions and new sources for this growing dangerous issue.


Soil is a Goldmine

Soil is one of the most microbially diverse environments on Earth. A single gram of soil can contain billions of bacteria and thousands of different species, many of which we still know very little about. These microbes are constantly competing with one another for nutrients and space, and one of their main survival strategies is producing antibiotic compounds to inhibit neighboring bacteria.


can you imagine just how much bacteria is in this picture??
can you imagine just how much bacteria is in this picture??

 
 
 

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University of New Hampshire at Manchester

Instructors: Dr. Sue Cooke & Sydney Rollins

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